Cornelia de Lange syndrome
Cornelia de Lange syndrome (CdLS) is a rare genetic disorder. Many people have never heard of it. It causes various physical, cognitive and medical challenges. Although no two children with this disorder are the same, there are many similarities in their appearance and behaviour. In 1933, the Dutch paediatrician Cornelia de Lange described two children with strikingly similar characteristics. The syndrome was therefore named after her. CdLS can manifest itself in different areas and individuals with CdLS can show specific physical, mental and behavioural characteristics. Mental characteristics are brain processes such as memory and thinking. Behavioural characteristics refer to certain behaviours that individuals with CdLS are more likely to display. These characteristics can vary greatly between individuals and range from small differences compared to other people to very noticeable differences. Our international panel of experts has compiled a comprehensive guide to the diagnosis and care
