NIPBL
The NIPBL gene codes for a protein which is part of the regulatory centre of cohesin and, along with another gene (MAU2) helps the ring to be loaded onto the duplicated DNA. Changes (mutations) in NIPBL can be found in approximately 70% of individuals with CdLS.
Classic CdLS is usually caused by changes in NIPBL.
order Topic Title Delete order Topic Title Delete order Topic Title Delete # Topic Title Delete 1 Congenital heart defects in NIPBL 2 What happens differently in the brain development of CdLS people with a mutation in NIPBL? 3 NIPBL # Topic Title Delete # Topic Title Delete 1 A Closer Look at NIPBL: Maya Topic Title Delete $lineArray[0]