NIPBL
The NIPBL gene codes for a protein which is part of the regulatory centre of cohesin and, along with another gene (MAU2) helps the ring to be loaded onto the duplicated DNA. Changes (mutations) in NIPBL can be found in approximately 70% of individuals with CdLS.
Classic CdLS is usually caused by changes in NIPBL.
order Titel Delete order Titel Delete order Titel Delete # Titel Delete 1 Congenital heart defects in NIPBL 2 What happens differently in the brain development of CdLS people with a mutation in NIPBL? 3 NIPBL # Titel Delete # Titel Delete 1 $lineArray[1] 2 A Closer Look at NIPBL: Maya Titel Delete $lineArray[0]