Mouth, nose and throat

        Para pais, prestadores de cuidados, prestadores de cuidados de saúde e professores, surgem frequentemente preocupações e questões relativas aos cuidados e bem-estar dos indivíduos com síndrome de Cornelia de Lange (CdLS). 

In individuals with CdLS, the nose is often characterised by a low, inward curving nasal bridge and easily visible nostrils. Recurrent sinus infections are common in CdLS and are thought to be caused by an atypically structured nose and impaired immune system.

Some individuals with CdLS have been reported to have soft, painless growths on the lining of their nasal passages or sinuses (nasal polyps).

They usually have a small mouth, small chin, short neck, stiff jaw joints and cleft palate. Therefore, anaesthesiologists should be made aware of the potential difficulty with intubation in individuals with CdLS before surgery.

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