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GI Medication Potency
Pergunta
Can GI medications lose their potency over time?
Resposta dos nossos peritos
All medicines lose their potency on the shelf after some time. They are dated, and should not be used after that time
Some medicines seem to lose their effectiveness in a patient after prolonged usage. Sometime the effect remains, but the side effect subsides. Sometimes medication interactions make it appear that the original medication is no longer working
DP/TK 7-13-10
Aprovado porClinical Advisory Board (CAB)
A resposta é verificada e válida para
Recomendação(ões)
Reflux
R32
Consider always gastro-oesophageal reflux disease (GORD) in any individual with CdLS owing to its frequency and wide variability in presentation, which includes challenging behaviour.
R33
Modification of nutrition and proton pump inhibitors (PPI) are the first-line treatments of GORD. Anti-reflux medications need to be used to their maximum dosage. Surgical interventions for GORD should be limited to those individuals with CdLS in whom nutritional and medical treatments have been unsuccessful or airway safety is at risk.
R34
If GORD symptoms persist, endoscopy should be strongly considered whilst an individual with CdLS is still in paediatric care.
R35
Surveillance for Barrett’s Oesophagus needs to be discussed with and decided together with the family, balancing the potential gain in health and burden for the individual with CdLS.
