Ask the expert


Precocious Puberty


My 8 year old daughter was diagnosed with precocious puberty. Her physician is recommending Lupron depot. Has this been effective with other girls with CdLS?

Answer of our experts

Precocious puberty occurs typically before age 8 in girls. Regarding the treatment, Lupron depot is the only depot treatment (long-acting, pulsatile) used in the US for precocious puberty when the cause is related to the activation of hormones from the brain (hypothalamus/pituitary gland). The treatment prevents the growth spurt to improve final adult height, and also somewhat treats the early puberty symptoms. If your daughter is followed by a pediatric endocrinologist, then I think everything sounds appropriate. I am not aware of this treatment previously in CdLS

TK 7-13-10

Answer is checked and valid for
Find other pages that share the same topic as this page Autonomic nervous system7 Autonomic nervous system21


Autonomic nervous system

Seizures in individuals with CdLS should be treated using the general management schemes.
An MRI of the brain should be considered only if the individual with CdLS shows neurological signs other than microcephaly (smaller than normal head).

Legal Disclaimer

Please take note that the Ask the Expert service is comprised of volunteer professionals in various areas of focus. Answers are not considered a medical, behavioral, or educational consultation. Ask the Expert is not a substitute for the care and attention your child’s personal physician, psychologist, educational consultant, or social worker can deliver.

Do you have a question you would like to ask?

Ask a Question

Do You urgently need help? Contact the CdLS Foundation USA, Our Staff!